We won’t dive too deeply into the science here, but the body has a number of pro-inflammatory mediators—i.e., cytokines, enzymes, and other messenger molecules—that modulate pro- vs. anti-inflammatory responses. Curcumin interacts with these key mediators to help regulate the body’s natural inflammatory response2. 

For example, curcumin has been found to directly bind to pro-inflammatory cytokines3, such as TNF alpha, IL-1 beta, and IL-6, and inhibit their expression.* Additionally, “curcumin reduces the activity of enzymes involved in inflammatory pathways—including COX-2, lipoxygenase, and inducible iNOS,” Jampolis explains.

We won’t dive too deeply into the science here, but the body has a number of pro-inflammatory mediators—i.e., cytokines, enzymes, and other messenger molecules—that modulate pro- vs. anti-inflammatory responses. Curcumin interacts with these key mediators to help regulate the body’s natural inflammatory response2. 

For example, curcumin has been found to directly bind to pro-inflammatory cytokines3, such as TNF alpha, IL-1 beta, and IL-6, and inhibit their expression.* Additionally, “curcumin reduces the activity of enzymes involved in inflammatory pathways—including COX-2, lipoxygenase, and inducible iNOS,” Jampolis explains.