Symbiome’s The One Cream has an even simpler INCI list, with just three powerful players: water, the aforementioned postbiotic lactobacillus ferment, and sanoma leaf oil. This fermented oil comes from the leaves of an Amazonian shrub that’s rich in lipids, phytosterols, and antioxidants—so it soothes and protects the skin. The Renewal Cleanser also contains sanoma leaf oil, along with seje and xanana fruit oils (other fermented bio oils), glycerin, plus gentle, moisturizing, plant-derived surfactants.