There are more than 80 types of autoimmune diseases, including Type I diabetes, arthritis, multiple sclerosis (also known as MS), and Graves’ disease. All of these come with their own unique symptoms. However, “The most common autoimmune disorder symptoms are fatigue, joint swelling and pain, skin issues, abdominal pain or digestive issues, and swollen glands,” explains board-certified regenerative medicine doctor Seema Bonney, M.D.