The connection between fertility and dehydroepiandrosterone (DHEA) has been a topic of research, particularly in the context of female fertility. But what is it and can it help improve the chances of conception?
We turned to the team at IVF Spain and asked them to explain….
DHEA is a natural steroid hormone produced by the adrenal glands and is a precursor to both male and female sex hormones, including estrogen and testosterone.
Several studies and clinical trials have explored the potential impact of DHEA supplementation on female fertility, especially in women with diminished ovarian reserve (DOR) or those undergoing fertility treatments such as in vitro fertilisation (IVF).
Here are some key points regarding the connection between fertility and DHEA:
Ovarian Function:
DHEA is thought to play a role in improving ovarian function. Some studies suggest that DHEA supplementation may enhance ovarian response to fertility treatments.
Improving Egg Quality:
One of the proposed mechanisms is that DHEA may improve egg quality, which is crucial for successful conception and healthy pregnancies.
Studies on DHEA and IVF:
Several small-scale studies and clinical trials have investigated the use of DHEA supplementation in women undergoing IVF, especially those with DOR. Some studies have reported positive outcomes, including increased pregnancy rates and live birth rates.
Individual Responses:
It’s important to note that individual responses to DHEA supplementation can vary. While some women may benefit, others may not experience the same positive effects.
Considerations and Cautions:
The use of DHEA for fertility purposes should be approached with caution. Long-term safety and potential side effects are not fully understood, and more research is needed.
Consultation with Healthcare Professionals:
Before considering DHEA supplementation for fertility, it’s crucial for individuals to consult with healthcare professionals, such as reproductive endocrinologists or fertility specialists. They can assess individual health conditions, provide personalised guidance, and monitor the use of DHEA.
Male Fertility:
While most research on DHEA and fertility has focused on women, there is limited evidence suggesting that DHEA might also have a positive impact on certain aspects of male fertility, such as sperm parameters. However, more research is needed in this area.
It’s important to emphasise that DHEA supplementation is not a one-size-fits-all solution, and its use should be carefully considered on an individual basis. The decision to use DHEA for fertility should be made in consultation with healthcare professionals who can provide guidance based on a person’s specific health history, fertility concerns, and treatment plan.
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