When you enter the fertility world, you’re forced to learn an entirely new language in order to understand your results, advocate for yourself, and communicate with your team. While it’s an important part of the process, it can also feel daunting. Here’s a crash course to help you feel more empowered.

In this article:

Becoming “fluent” in fertility speak helps you communicate more easily with your Care Team, advocate for yourself, and feel more confident during each step of the process.

When you’re already taking in so much new information, having the vocabulary to ask the right questions and understand answers from your physician, nurse, and other team members can make a big difference. 

Remember: Your team will always be happy to explain these terms when needed if you forget what they mean, so don’t be afraid to ask for clarification. They’re there to help!

A term commonly used by the fertility community at large (both by those pursuing fertility treatment and those attempting pregnancy on their own) to describe focused efforts to conceive a baby. 

Semen Analysis (SA)

Examination of male ejaculate under a microscope to determine the number of sperm, their ability to move forward (motility) and their shape (morphology).

Semen analysis is an essential part of fertility testing, particularly in couples experiencing infertility. Sperm count, motility and morphology all provide important information about how the sperm will perform in treatment cycles.

Basal Body Temperature (BBT)

This is your body’s temperature at rest which can be taken each morning before getting out of bed. BBT is measured orally each morning and recorded on a calendar chart. These charts can help identify the time of ovulation in people with regular cycles. 

Ovulation Predictor Kit (OPK)

An OPK is a home test that checks your urine to predict when you’re most likely to be fertile. When your body is preparing to ovulate (release an egg), it produces more luteinizing hormone (LH) which is what OPKs detect.

Note: If you have a condition such as PCOS, it’s important to know that OPKs test urine for a surge in luteinizing hormone (LH), which increases as you approach ovulation. Many PCOS patients have high levels of LH, which could falsely indicate ovulation. The bottom line – getting bloodwork done is the most accurate way to track ovulation.

Birth Control Pill (BCP)

A daily medication containing hormones that prevent pregnancy. Also used during fertility treatment cycles. In the video below, Nurse Practitioner Monica Moore explains why we use BCPs for patients who are trying to conceive (we know it can be confusing).

Note: Learn more about HSGs with our “What to Expect” guide.

Saline Infusion Sonohysterogram (SIS or SHG)

Saline infusion sonohysterography (SIS or SHG) is a procedure to evaluate the state of the uterus and shape of the uterine cavity, and detect any abnormalities. Using ultrasound and sterile saline fluid, the uterus and uterine lining are closely examined to ensure the environment is healthy and optimal for a future pregnancy.

Note: Learn more about SHGs with our “What to Expect” guide.

Endometrial Receptivity Analysis (ERA)

A special test performed during some IVF cycles to help determine whether the endometrium is receiving an embryo at the right time in an attempt to maximize chances of a successful pregnancy and live birth.

A technique for identifying genetic or chromosomal information about embryos before transferring them into the uterus to achieve a pregnancy. There are three different types of PGT (see below). Learn more about PGT here.

Note: PGT is different from genetic carrier testing, which is performed on the intended parents to screen for genetically-inherited disorders or chromosomal abnormalities.

Preimplantation Genetic Testing for Aneuploidies (PGT-A)

PGT-A identifies aneuploidy, the term used to describe any embryo with either too many or too few chromosomes (or large extra or missing pieces of chromosomes). One form of aneuploidy causes Down Syndrome, and other chromosomal changes may cause up to 60% of miscarriages or prevent pregnancy altogether.

Preimplantation Genetic Testing for Monogenic/Single-Gene Disorders (PGT-M)

PGT-M tests for monogenic (single gene) disorders, such as Cystic Fibrosis, Huntington’s disease, Sickle Cell Anemia, muscular dystrophy, and hemophilia – detection that is especially important for people who know their families carry the defective gene.

Preimplantation Genetic Testing for Chromosomal Structural Rearrangements (PGT-SR)

PGT-SR looks for structural rearrangements when a parent is known to carry a chromosome change such as a translocation or inversion. These can cause extra or missing chromosomal material in embryos.

ART includes all clinical and laboratory treatments in which either eggs or embryos are handled with the intent to result in a pregnancy (for example, IUI and IVF).

Intracytoplasmic Sperm Injection (ICSI)

Placement of a single sperm into a single oocyte (egg) by penetrating the outer coating of the egg. This technique is used in cases with low sperm count, motility or morphology. ICSI is also used for patients who have had previous IVF cycles with failed fertilization.

Testicular/Epididymal Sperm Aspiration (TESA)

The surgical removal of sperm directly from the testes or the epididymis using a needle for aspiration. This procedure is used for men who have no sperm in their ejaculate or have had vasectomies in the past.

Sperm obtained through TESE requires ICSI to ensure fertilization of the oocyte (egg).

Vaginal Oocyte Retrieval (VOR)

The medical term for an egg retrieval during an IVF cycle.

Note: Learn more about the egg retrieval procedure with our “What to Expect” guide.

Ovarian Hyperstimulation Syndrome (OHSS)

A potential side effect of taking fertility medication during an IVF treatment cycle. Learn more about OHSS here.

Intrauterine Insemination (IUI)

IUI is a technique that transfers sperm directly into the uterus, bypassing the vaginal and cervical defense mechanisms of the female reproductive tract to allow for better sperm delivery to the fallopian tubes. 

Learn more: Get your comprehensive guide to IUI treatment here!

In Vitro Fertilization (IVF)

A common fertility treatment method that involves stimulating the ovaries to produce a large number of follicles, an egg retrieval procedure, fertilization of those eggs with designated sperm in the lab, embryo growth monitoring, and embryo transfer once the intended parents are ready to attempt pregnancy.

Learn more: Explore IVF treatment with this step-by-step guide from a fertility nurse.

Assisted Hatching (AH)

Assisted hatching is a procedure used in IVF treatment that can help the embryo “hatch” from its “shell” by creating a small crack in the zona pellucida (the transparent membrane surrounding the egg).

It is believed that assisted hatching can help an embryo implant in the uterus, leading to higher pregnancy rates in some patients.

Reciprocal In Vitro Fertilization (RIVF)

This treatment method is similar to traditional IVF, except that one female partner’s eggs are retrieved and fertilized, with the resulting embryos being transferred into the second female partner to attempt pregnancy.

Explore other LGBTQ+ family-building options and resources for your journey with our resource hub, Gay Parents To Be or read one couple’s RIVF story here.

Elective Single Embryo Transfer (ESET)

The process of only transferring one embryo into the uterus (versus transferring multiple embryos at once). It is now considered best practice in IVF treatment to only transfer one embryo at a time to ensure the safest pregnancy possible and best outcome for baby. 

Gestational Carrier (GC)

Also referred to as a gestational surrogate (or simply a surrogate), a gestational carrier is a woman who carries and delivers a child for another couple or individual (the intended parents). When using a GC, the eggs used to create the embryos come from a different egg donor source, not the GC.

Learn more: Read Tim & Steve’s surrogacy story to hear about working with a GC.

Frozen Embryo Transfer (FET)

An embryo transfer using frozen embryos that have been thawed from a previous IVF cycle.

The number of days after an embryo transfer in an IVF treatment cycle.

Two-Week Wait (TWW or 2WW)

The window of time between ovulation and a missed period when you’re waiting to take a pregnancy test. This term is also frequently used to indicate the span of time between embryo transfer and your “official” pregnancy test bloodwork at your fertility clinic (though it won’t be a full two weeks – usually around 9-10 days after transfer). 

Get support for navigating the two-week wait from Brigitte, one of our fertility nurses.

Last Menstrual Period (LMP)

The first day (onset of full flow bleeding) of your last menstrual period before becoming pregnant.

Estimated Due Date (EDD)

The estimated date of delivery calculated based on conception date.

Dilation & Curettage (D&C)

A surgical procedure in which the cervix is dilated (expanded) so that the uterine lining can be scraped with a curette (spoon-shaped instrument) to remove abnormal tissue or remnants from a miscarriage.

Learn more about the D&C procedure with this guide.

A common endocrine disorder that causes hormonal imbalances in women of reproductive age. It can lead to dysfunctional ovulation, fertility issues, weight gain, insulin resistance (pre-diabetes) and an increase in the male hormone, testosterone. 

Diminished Ovarian Reserve (DOR)

A condition in which the ovaries lose their normal reproductive potential, leading to reduced fertility and an increase in trouble getting pregnant due to a loss of quality and/or quantity eggs available for fertilization.

10-30% of patients presenting to doctors with infertility struggle with DOR.

Read about one woman’s journey with DOR to learn more.

Want to learn even more? Explore RESOLVE’s Fertility Acronyms dictionary.

• Take a notepad with you to jot down answers or follow-up questions
• Prepare ahead of time and bring a list of questions with you
• Ask your doctor to slow down or repeat something if needed
• Have someone you trust attend the appointment with you and be a second pair of ears
• Email or call your Care Team after the appointment for further clarification

Illume Fertility offers free, one-on-one fertility support via our Patient Advocate, Lisa Rosenthal, who is a former fertility patient herself. You don’t even need to be an Illume patient!

If you’re having a difficult time communicating with your Care Team, have concerns about your treatment or are experiencing other challenges related to family building, reach out to Lisa at 203-354-1157 or email lrosenthal@illumefertility.com.